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Posts Tagged ‘Advances in Genome Biology and Technology’


Tuesday, February 23rd, 2010

AGBT Workshop: “Enrichment of Resequencing Targets for Analysis of Rare Variants”

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“Enrichment of Resequencing Targets for Analysis of Rare Variants”

Presented by RainDance Technologies

at the 11th Annual Advances in Genome Biology and Technology (AGBT) Meeting

Despite notable success in the identification of common variants using genome-wide association studies, these approaches often lack the resolution to identify a large portion of the total variation believed to contribute to disease. With an increased interest in understanding the contribution of variants with a range of frequency and effect, high-resolution methods such as targeted resequencing provide the opportunity to assay both common and rare variants in large cohort studies. In order to confidently detect rare variants, it is critical to obtain as complete coverage as possible for regions of interest.

RainDance Technologies has commercialized a platform to enable the most complete coverage of resequencing targets by leveraging the benefits of single-molecule PCR in a format that easily integrates into next-generation sequencing workflows. To explain the benefits of this approach, RainDance will hold an AGBT workshop, entitled “Enrichment of Resequencing Targets for Analysis of Rare Variants.”

The Sequence Enrichment application utilizes our RainStorm™ technology to manipulate picoliter volume droplets to generate more than two million independent PCR reactions per sample in a simple and robust process. The workshop will describe the use of this novel method for enrichment of resequencing targets with high efficiency resulting in the highest-quality data for analysis of rare variants in both coding and non-coding regions of the genome. In addition, the workshop will feature a preview of new applications from RainDance that include targeted methylation analysis and ultra-deep resequencing of heterogeneous samples.

Enrichment of Resequencing Targets for Analysis of Rare Variants
February 26, 2010
2:00 to 3:00 p.m. EST
Marco Island Marriott Resort, in the Islands Ballroom

Speakers:

  • Scott Kennedy, Chief Scientific Officer
  • Roopom Banerjee, President & CEO
  • Guest Speaker:  Dale J. Hedges, Ph.D., Assistant Professor of Human Genetics, Assistant Director, Center for Genome Technology, Hussman Institute for Human Genomics (HIHG), Miller School of Medicine, University of Miami

More information about the workshop: http://www.raindancetech.com/agbt/

For more information about RainDance Technologies, please visit www.raindancetech.com.

Follow RainDance  Technologies on Twitter at http://twitter.com/RainDanceTech

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Public Relations contact, Boston: Don Goncalves, dgoncalves@tizinc.com, 781-793-9380, for Tiziani Whitmyre Inc., http://www.tizinc.com/public-relations

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Friday, January 30th, 2009

“Enrichment of Genomic Loci for Targeted Sequencing Application” Is Focus of 2009 AGBT Conference Workshop

LEXINGTON, Massachusetts, USA –January 30, 2009 – Jeff Olson, Manager of Nucleic Acid Applications, of RainDance Technologies, Inc., will present “Enrichment of Genomic Loci for Targeted Sequencing Applications,” to explain application of the RainStorm micro-droplet technology on the new RDT 1000 instrument, at the 2009 Advances in Genome Biology and Technology (AGBT) conference on Friday, February 6th, in Marco Island, Florida.

RainDance Technologies is a provider of innovative microdroplet-based solutions which enable and benefit biological applications utilized in human health and disease research.

“Recent advances in DNA sequencing technologies have improved accuracy and dramatically reduced cost. However, even with the improved efficiency of “second generation” systems, sequencing thousands of human genomes across various phenotypes is still economically unrealistic. To exploit the full potential of new sequencing techniques, a robust method for isolating biologically relevant genomic loci on the megabase scale will be required,” said Olson.

Olson has more than twenty years of experience in molecular biology, technology development and DNA diagnostics. He manages the Nucleic Acids Applications group at RainDance Technologies (http://www.raindancetech.com/) and is responsible for the development of the company’s Sequence Enrichment application.

Olson will present “Enrichment of Genomic Loci for Targeted Sequencing Applications” at the 2009 AGBT meeting on Friday, February 6th, at 2:00 p.m. in the Islands Ballroom at the Marco Island Marriott Resort, Golf Club & Spa, Florida.

The 2009 Advances in Genome Biology and Technology conference (http://www.agbt.org/), a premier scientific forum for capturing the latest advances in new DNA sequencing technologies and for presentations on the applications of genomics to diverse areas in biology and biomedicine, runs February 4-7, 2009.

About RainDance Technologies
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s RainStorm™ technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimize process-induced bias or error.

RainDance’s initial application will focus on the targeted sequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

RainStorm™ is a trademark of RainDance Technologies, Inc.

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Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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