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Posts Tagged ‘genomics’


Tuesday, March 17th, 2009

RainDance Technologies Reviews Opportunities for Growth at Cowen Health Care Conference

BOSTON, MASSACHUSETTS, U.S.A., March 17, 2009 — RainDance Technologies, Inc., a privately held provider of innovative microdroplet-based solutions for human health and disease research, today announced it will be shipping its first commercial Sequence Enrichment Solution this month and reviewed the company’s opportunities for growth at Cowen and Company’s 29th Annual Health Care Conference.

The initial application of the company’s RainStorm(TM) microdroplet-based technology platform focuses on targeted sequencing of the human genome, one of the fastest-growing segments of the rapidly expanding $1 billion DNA sequencing market. The company’s Sequence Enrichment Solution and RDT 1000 system will enable the high-resolution analysis of genetic variation between individuals within populations at a level unmatched by current methodologies.

“We will make the first commercial shipment of our Sequence Enrichment Solution in March and presently have a backlog of orders,” said Chris McNary, President and Chief Executive Officer, RainDance Technologies. “Over the next 3 years, we estimate the genomic sequence enrichment market at about $400 million, and we believe RainDance can capture a significant share.”

During the last 6 months, RainDance has provided its solution to early access partners representing some of the world’s leading genome research centers. These include the J. Craig Venter Institute, The Genome Center at the Washington University School of Medicine, and the Broad Institute. The company also collaborated with the Scripps Translational Science Institute to accelerate targeted genomic sequencing in its Wellderly Study of America’s healthy elderly.

In targeted DNA sequencing applications, the Sequence Enrichment Solution provides researchers with higher resolution and statistical power while maximizing workflow efficiency and cost. “Our solution enables one next-generation sequencer to do what alternative technologies would require seven sequencers to complete in the same time,” said McNary.

The company also reviewed the application of its RainStorm technology across a wide variety of growing life sciences and applied sciences markets.

“We have announced a consortium with sanofi aventis and Université Louis Pasteur to develop the next generation of high-throughput screening and small molecule compound storage for drug discovery — a $4 billion market,” said McNary.

RainDance recently shared in a Massachusetts Life Sciences Center grant of $250,000 per year for 3 years to Dr. David Weitz, Mallinckrodt Professor of Physics and Applied Physics at Harvard’s School of Engineering and Applied Sciences and Physics Department. The grant will fund research to develop a new form of fluorescence-activated cell sorter used to collect biochemical information about individual cells.

“We also have demonstrated proof of principle of our droplet-based technology in enzymatic detection of cell surface markers, sorting based on secreted proteins from cells, immunoassays, qPCR, and enzyme-directed evolution for industrial and biofuel applications,” he said. “These studies highlight the potential of our RainStorm technology to become a true platform capable of sustaining growth for years to come.”

About RainDance Technologies, Inc.
RainDance Technologies, Inc., is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s RainStorm technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

# # #

RainStorm(TM) is a trademark of RainDance Technologies, Inc.
Public Relations contact: Tiziani Whitmyre Inc., http://www.tizinc.com/

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Posted in Biosciences |


Monday, February 16th, 2009

RainDance Technologies Appoints Patrick Kelly As European Sales Director

LEXINGTON, MASSACHUSETTS, U.S.A., February 16, 2009 – RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, has appointed Patrick Kelly to the newly created position of European Sales Director, effective immediately.

“Mr. Kelly’s appointment represents an important step in the geographic expansion of our commercial efforts with the first quarter release of our Sequence Enrichment Solution for the targeted sequencing of the human genome,” said Stephen E. Becker, Vice President, Commercial Operations, RainDance Technologies. “His international business experience in life sciences and genetics and sequencing makes him the ideal candidate to lead RainDance’s entry into the European market.”

Based in Manchester, England, Mr. Kelly will be responsible for introducing RainDance’s RainStormTM technology platform to Europe. He will work with thought leaders in genomics research to adopt RainDance’s Sequence Enrichment Solution and the RDT 1000 instrument. In addition, Mr. Kelly will build the commercial sales infrastructure required to launch the company’s solutions in the European market.

Mr. Kelly joins RainDance from Helicos Biosciences where he served as Global Business Manager for the company’s European operations. In this role, he led the positioning of the company’s next-generation sequencing technology with opinion leaders in the region. Mr. Kelly previously was Business Team Manager, Europe, Middle East, Africa, for Agilent Technologies. He also was European Site Manager and Vice President, Sales and Support, for Affymetrix Europe, where he led commercial activities for microarray systems and reagents in the research, pharmaceutical, and molecular diagnostics markets, and served as European Sales Manager for genetic analysis systems at Applied Biosystems. Mr. Kelly received a Bachelor of Science degree in Chemistry from Sheffield University and is a member of the Institute of Directors (UK).

About RainDance Technologies, Inc.
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s RainStormtm technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance’s initial application will focus on the targeted sequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

# # #

RainStorm(TM) is a trademark of RainDance Technologies, Inc.
Public Relations contact: Tiziani Whitmyre Inc., http://www.tizinc.com/

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Posted in Biosciences |


Wednesday, February 4th, 2009

RainDance Technologies Announces Commercial Release of its Sequence Enrichment Solution

LEXINGTON, MASSACHUSETTS, U.S.A., February 4, 2009 — RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today announced the commercial release of its Sequence Enrichment Solution for sales in North America.

In an announcement at the 2009 Advances in Genome Biology and Technology Conference (AGBT), the company said it has begun accepting orders for the solution and has started commercial production of the solution’s components for shipment during the first quarter.

“This milestone represents the first commercialized application of our exciting RainStorm(TM) microdroplet-based technology platform,” said Chris McNary, President and Chief Executive Officer of RainDance Technologies. “It underscores the power of droplet-based biology to increase the depth of understanding about biological problems and increase the pace of biomedical discovery.”

The RainDance Sequence Enrichment Solution incorporates RainStorm technology for targeted sequencing applications of the human genome. It will enable the high-resolution analysis of genetic variation between individuals within populations at a level unmatched by current methodologies. The solution dramatically improves sample uniformity and reduces the selection bias typically associated with targeted sequencing.

The Sequence Enrichment Solution consists of the following components:
The RDT 1000 system generates picoliter-volume discrete PCR reactions in droplets at the unprecedented rate of 10 million per hour. It amplifies hundreds to thousands of genomic loci with high specificity and uniformity.
Custom-Order Content for DNA Primer Libraries will be available that enable the amplification of hundreds to thousands of genomic loci in a single tube. RainDance customers can design and order these libraries specifically for their research applications.
Sequence enrichment consumables kits, provide a complete workflow solution for easy implementation in the laboratory.

The company also announced that comprehensive training and support services are available to maximize the operating performance of the solution.

“This commercialization step is the culmination of a rigorous Early Access Partner program that involved some of the world’s leading genomic research institutions,” said McNary. “These organizations see the potential of our Sequence Enrichment Solution to enhance the performance of their next-generation sequencing platforms and accelerate their discovery process.”

RainDance also is presenting a workshop, “Enrichment of Genomic Loci for Targeted Sequencing Applications,” at the AGBT Conference on February 6 to explain the application and benefits of its new technology in genomics research.

For sales information, contact info@raindancetech.com or call 781-861-6300. The company said the Sequence Enrichment Solution will be available for purchase in Europe later this year.

About RainDance Technologies, Inc.
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s RainStormtm technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance’s initial application will focus on the targeted sequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

RainStorm(TM) is a trademark of RainDance Technologies, Inc.

# # #

Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Friday, January 30th, 2009

“Enrichment of Genomic Loci for Targeted Sequencing Application” Is Focus of 2009 AGBT Conference Workshop

LEXINGTON, Massachusetts, USA –January 30, 2009 – Jeff Olson, Manager of Nucleic Acid Applications, of RainDance Technologies, Inc., will present “Enrichment of Genomic Loci for Targeted Sequencing Applications,” to explain application of the RainStorm micro-droplet technology on the new RDT 1000 instrument, at the 2009 Advances in Genome Biology and Technology (AGBT) conference on Friday, February 6th, in Marco Island, Florida.

RainDance Technologies is a provider of innovative microdroplet-based solutions which enable and benefit biological applications utilized in human health and disease research.

“Recent advances in DNA sequencing technologies have improved accuracy and dramatically reduced cost. However, even with the improved efficiency of “second generation” systems, sequencing thousands of human genomes across various phenotypes is still economically unrealistic. To exploit the full potential of new sequencing techniques, a robust method for isolating biologically relevant genomic loci on the megabase scale will be required,” said Olson.

Olson has more than twenty years of experience in molecular biology, technology development and DNA diagnostics. He manages the Nucleic Acids Applications group at RainDance Technologies (http://www.raindancetech.com/) and is responsible for the development of the company’s Sequence Enrichment application.

Olson will present “Enrichment of Genomic Loci for Targeted Sequencing Applications” at the 2009 AGBT meeting on Friday, February 6th, at 2:00 p.m. in the Islands Ballroom at the Marco Island Marriott Resort, Golf Club & Spa, Florida.

The 2009 Advances in Genome Biology and Technology conference (http://www.agbt.org/), a premier scientific forum for capturing the latest advances in new DNA sequencing technologies and for presentations on the applications of genomics to diverse areas in biology and biomedicine, runs February 4-7, 2009.

About RainDance Technologies
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s RainStorm™ technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimize process-induced bias or error.

RainDance’s initial application will focus on the targeted sequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

RainStorm™ is a trademark of RainDance Technologies, Inc.

# # #


Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Wednesday, December 10th, 2008

RainDance Technologies Delivers RDT 1000, Sequence Enrichment Solution to Broad Institute

LEXINGTON, MASSACHUSETTS, U.S.A., December 10, 2008 — RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today announced that the Eli and Edythe L. Broad Institute in Cambridge, Massachusetts, will become an early access partner for its new RDT 1000 and Sequence Enrichment Solution.

Under the Early Access Partner program, RainDance will deliver to the Broad Institute its RDT 1000, consumables kits, and expert training for sequence enrichment. This will include custom PCR primer libraries designed to selectively amplify loci of interest for the Institute’s breakthrough genomic research initiatives. In addition, the Institute will investigate the application of the RDT 1000 for experiments related to the human microbiome.

“The program provides an opportunity for some of the world’s leading scientists in genomic research to become experienced with our technology months prior to its commercial launch,” said Chris McNary, President and Chief Executive Officer of RainDance Technologies. “Their work also represents further recognition of our platform’s unique capabilities to extend into other targeted sequencing applications of significant biological importance.”

The RDT 1000 and Sequence Enrichment Solution utilize RainDance’s breakthrough RainStormTM microdroplet-based technology platform. The simplicity and speed of the technology are designed to maximize the efficiency of next-generation DNA sequencing workflows. The RDT 1000 generates picoliter volume PCR reactions at the rate of 10 million discrete reactions per hour. The high-speed sample processing is further enhanced by the fact that the Sequence Enrichment Solution utilizes a library of PCR primers in droplets enabling the amplification of hundreds to thousands of genomic loci in a single tube. The RainStorm format avoids the limitations of traditional multiplex hybridization and amplification technologies. RainDance’s solution minimizes process-induced bias or error and requires only a few micrograms of genomic DNA.

“We are anticipating our solution will significantly enhance the Broad Institute’s genomics research program,” said McNary. “It is our expectation their experience will further reinforce the benefits of our solution in biomedical research.”

About RainDance Technologies, Inc.
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance’s initial application will focus on the targeted resequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

# # #

Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Wednesday, November 12th, 2008

RainDance Technologies Introduces Sequence Enrichment Solution

PHILADELPHIA, PENNSYLVANIA, USA, November 12, 2008 — RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today officially introduced its Sequence Enrichment Solution for targeted sequencing applications of the human genome.

RainDance unveiled the solution at the 58th Annual Meeting of the American Society of Human Genetics (ASHG) in Philadelphia, Penn.

“The RainDance Sequence Enrichment Solution represents a true paradigm shift forward in the sequencing of targeted regions of the human genome,” said Chris McNary, President and Chief Executive Officer of RainDance Technologies.

“Our solution will enable the high-resolution analysis of genetic variation between individuals within populations at a level unmatched by current methodologies. It dramatically improves sample uniformity and reduces the selection bias typically associated with targeted sequencing,” McNary said.

Targeted sequencing is one of the fastest growing applications for next-generation sequencing technology. Sequence enrichment is a critical step in an efficient targeted sequencing workflow. The RainDance Sequence Enrichment Solution allows researchers to isolate specific regions of the genome for subsequent sequencing.

The RainDance Sequence Enrichment Solution consists of the following:

The RDT 1000, also introduced today at ASHG, generates picoliter volume discrete PCR reactions in droplets at the unprecedented rate of 10 million per hour. It amplifies hundreds to thousands of genomic loci with high specificity and uniformity.

Customer-Specified DNA Primer Libraries enable the amplification of hundreds to thousands of genomic loci in a single tube. RainDance clients will design and order these libraries specifically for their research applications.

Reagents, consumables, and services provide a complete workflow solution implemented in the laboratory.

“The Sequence Enrichment Solution minimizes errors and maximizes the efficiency of PCR by leveraging the sensitivity and specificity of this proven methodology while avoiding the limitations of alternative multiplex hybridization and amplification techniques,” said McNary.

“It significantly reduces study time and costs while requiring only a few micrograms of sample DNA. Researchers can utilize our solution to either significantly shorten study time, or to enhance study quality by generating additional samples in the same time within the same research budget,” he said.

The solution fits seamlessly into any workflow and dramatically improves process output and data quality. Its “open” design easily integrates with all next-generation DNA sequencing platforms.

The company plans to commercially launch the solution during the first quarter of 2009.

Under RainDance’s Early Access Partner program, the RainDance Sequence Enrichment Solution has been delivered and is in use at selected premier organizations engaged in genomic research, including The Genome Sequencing Center (GSC) at the Washington University School of Medicine in St. Louis, Missouri, and the J. Craig Venter Institute (JCVI) in Rockville, Maryland.

For more information about RainDance Technologies and its revolutionary new Sequence Enrichment Solution and RDT 1000, visit booth 825 at ASHG 2008, or the company’s website at www.raindancetech.com.

About RainDance Technologies, Inc.
RainDance Technologies, Inc. is a provider of innovative microdroplet-based biological solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England; and the ESPCI in Paris. For more information, visit www.raindancetech.com.

# # #

Download high resolution images from: www.flickr.com/photos/10956940@N08/sets/72157608504468068/

Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Wednesday, November 12th, 2008

RainDance Technologies Introduces the RDT 1000

PHILADELPHIA, PENNSYLVANIA, USA, November 12, 2008 — RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today officially introduced its new RDT 1000, the centerpiece of its Sequence Enrichment Solution for the targeted genomic sequencing market.

RainDance unveiled the RDT 1000 at the 58th Annual Meeting of the American Society of Human Genetics (ASHG) in Philadelphia, Penn.

“We believe the RDT 1000 represents a breakthrough in accelerating the sequencing of targeted regions of the human genome,” said Chris McNary, President and Chief Executive Officer of RainDance Technologies. “It delivers exceptionally high sequencing efficiency, enabling reduced workflow costs and faster time to results.”

Targeted sequencing is one of the fastest growing applications for next-generation sequencing technology. Sequence enrichment is a critical step in an efficient targeted sequencing workflow. The RainDance Sequence Enrichment Solution allows researchers to isolate specific regions of the genome for subsequent sequencing.

The RDT 1000, with RainStorm(TM) microdroplet-based technology, amplifies hundreds to thousands of genomic loci with high specificity and uniformity. It leverages the sensitivity and specificity of polymerase chain reaction (PCR) methodology, a tested and trusted process in laboratories worldwide, while avoiding the limitations of alternative multiplex hybridization and amplification techniques. The RDT 1000 generates replicate reactions to minimize error and ensure confidence in sequencing results.

“Researchers can utilize the RDT 1000 to either greatly reduce study time, or to improve study quality by running more samples in the same time within the same research budget,” said McNary.

The RDT 1000 fits seamlessly into any targeted sequencing workflow and dramatically improves process output and data quality. It maximizes the efficiency of the workflow by minimizing the requirement to perform additional sequencing to ensure adequate coverage for the loci of interest.

“The RDT 1000’s ‘open’ design easily integrates with all next-generation DNA sequencing platforms,” McNary said.

Under RainDance’s Early Access Partner program, the RDT 1000 has been delivered and is in use at selected premier organizations engaged in genomic research, including The Genome Sequencing Center (GSC) at the Washington University School of Medicine in St. Louis, Missouri, and the J. Craig Venter Institute (JCVI) in Rockville, Maryland.

RainDance plans to commercially launch the RDT 1000 in the first quarter of 2009.

To learn more about RainDance Technologies and its revolutionary new RDT 1000 and Sequence Enrichment Solution, visit booth 825 at ASHG 2008, or the company’s website at http://www.raindancetech.com/.

About RainDance Technologies, Inc.
RainDance Technologies, Inc. is a provider of innovative microdroplet-based biological solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England; and the ESPCI in Paris. For more information, visit http://www.raindancetech.com/.

# # #

Download high resolution images from: www.flickr.com/photos/10956940@N08/sets/72157608504468068/

Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Thursday, November 6th, 2008

RainDance Technologies Delivers RDT 1000, Sequence Enrichment Solution to The Genome Center at Washington University School of Medicine in St. Louis

LEXINGTON, MASSACHUSETTS, U.S.A., November 6, 2008 — RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today announced that it has shipped its new RDT 1000 instrument and Sequence Enrichment application to The Genome Center (GC) at the Washington University School of Medicine in St. Louis, a world leader in genomics research.

Under RainDance’s Early Access Partner program, RainDance will provide its new RDT 1000 and expert training to the GC, along with customized PCR primer libraries to selectively amplify loci of interest for their research initiatives.

Elaine Mardis, Ph.D., Co-Director of The Genome Center, said GC researchers “will be applying the platform in our large-scale targeted sequencing studies and are enthusiastic about reporting their experiences and results.”

“If the technology delivers as promised, RainDance Technology stands to significantly advance the art of targeted sequencing,” Dr. Mardis said.

“As a leader in advancing genome sequencing and its application to human health, we’re very excited about the participation of the GC in our Early Partnership Program. Their input and experience will be invaluable as we introduce the RainStorm platform to the world’s DNA sequencing market,” said Chris McNary, President and Chief Executive Officer of RainDance Technologies.

RainDance plans to commercially launch the RainDance platform in the first quarter of 2009, McNary added.

The RDT 1000 and Sequence Enrichment application utilize RainDance’s breakthrough RainStorm droplet-based technology platform. The simplicity, speed, and minute volume of the technology are designed to maximize the efficiency of next-generation DNA sequencing workflows. The RDT 1000 generates picoliter volume PCR reactions at the rate of 10 million discrete reactions per hour. The high-speed sample processing is further enhanced by the fact that the Sequence Enrichment application utilizes a library of PCR primers in droplets enabling the amplification of hundreds to thousands of genomic loci in a single tube. The RainStorm format avoids the limitations of traditional multiplex hybridization and amplification technologies. RainDance’s solution minimizes process-induced bias or error and requires only a few micrograms of genomic DNA.

About RainDance Technologies, Inc.
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance’s initial application will focus on the targeted resequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

# # #

Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Monday, November 3rd, 2008

RainDance Technologies to Present Workshop on Sequence Enrichment Using Innovative Microdroplet-Based Solutions at ASHG 2008

LEXINGTON, MASS. – November 3, 2008 – RainDance Technologies will present a workshop on sequence enrichment using innovative microdroplet-based solutions at the American Society of Human Genetics (ASHG) 58th Annual Meeting in Philadelphia on Thursday, November 13th.

Recent advances in DNA sequencing technologies have improved accuracy and dramatically reduced cost. However, even with the improved efficiency of “second generation” systems, sequencing thousands of human genomes across various phenotypes is still economically unrealistic. To exploit the full potential of new sequencing techniques, a robust method for isolating biologically relevant genomic loci on the megabase scale will be required.

Analogous to what the massively parallel sequencing technologies have done to improve the efficiency of DNA sequencing, RainDance Technologies has developed a platform to enable the use of PCR for high-throughput amplification of targeted genomic sequences.

The workshop at ASHG 2008 will explain the application of this new technology.

“The Sequence Enrichment application leverages our RainStorm™ technology to manipulate picoliter volume droplets in disposable chips. We will present the use of this novel method for enrichment of genomic loci with minimal selection bias prior to sequencing, demonstrating the utility of this approach for the routine application of targeted sequencing,” said Jeff Olson, Manager of Nucleic Acid Applications, RainDance Technologies. Olson will lead the workshop.

To register for the workshop, “Sequence Enrichment Using Droplet-Based Microfluidics,” visit: www.raindancetechnologies.com/ashgworkshop. The workshop will be held at the American Society of Human Genetics (ASHG) 58th Annual Meeting, Thursday, November 13, 2008, from 1:00 -2:00 p.m. at the Philadelphia Marriott, 4th floor, Room 411.

To learn more about RainDance Technologies and its revolutionary new RainStorm™ innovative microdroplet-based technology, visit booth 825 at ASHG 2008, or the company’s website at http://www.raindancetech.com/.

About RainDance Technologies, Inc.
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance’s initial application will focus on the targeted resequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

# # #

Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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Posted in Biosciences |


Monday, November 3rd, 2008

RainDance Technologies Delivers RDT 1000, Sequence Enrichment Solution to JCVI

LEXINGTON, MASSACHUSETTS, U.S.A., October 30, 2008 — RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today announced that the J. Craig Venter Institute (JCVI), a not for profit genomic research organization located in Rockville, MD and La Jolla, CA, will become an early access partner for its new RDT 1000 instrument and Sequence Enrichment application.

Under the Early Access Partner program, RainDance delivers its RDT 1000 and expert training to selected premier organizations in genomic research. RainDance will also provide customized PCR primer libraries designed to selectively amplify loci of interest for research initiatives at JCVI. “The program provides an opportunity for some of the world’s leading scientists in genomic research to become experienced with our technology prior to our commercial launch,” said Chris McNary, President and Chief Executive Officer of RainDance Technologies.

The RDT 1000 and Sequence Enrichment application utilizes RainDance’s breakthrough RainStorm™ droplet-based technology platform. The simplicity, speed, and minute volume of the technology are designed to maximize the efficiency of JCVI’s next-generation DNA sequencing workflow. The RDT 1000 generates picoliter volume PCR reactions at the rate of 10 million discrete reactions per hour. The high-speed sample processing is further enhanced by the fact that the Sequence Enrchment application utilizes a library of PCR primers in droplets enabling the amplification of hundreds to thousands of genomic loci in a single tube. The RainStorm format avoids limitations of traditional multiplex hybridization and amplification technologies. The RainDance solution minimizes process-induced bias or error and requires only a few micrograms of genomic DNA.

JCVI scientists “will incorporate the RainStorm application into the various large-scale targeted sequencing studies as part of our on-going research programs in human genomic medicine,” said Robert L. Strausberg, Ph.D., Deputy Director and Group Leader, Genomic Medicine, JCVI.

“We are looking forward to working closely with JCVI as they integrate our technology to support their breakthrough research,” McNary said. “We’re also anxiously anticipating the results of the performance of our technology in their hands”. It is our expectation their experience will further reinforce the RainStorm technology platform’s benefits in human health and disease research,” he said.

“This expert experience will be invaluable as we prepare for our commercial launch in the first quarter of 2009,” McNary added.

About the J. Craig Venter Institute
The JCVI is a not-for-profit research institute in Rockville, MD and La Jolla, CA dedicated to the advancement of the science of genomics; the understanding of its implications for society; and communication of those results to the scientific community, the public, and policymakers. Founded by J. Craig Venter, Ph.D., the JCVI is home to approximately 400 scientists and staff with expertise in human and evolutionary biology, genetics, bioinformatics/informatics, information technology, high-throughput DNA sequencing, genomic and environmental policy research, and public education in science and science policy. The legacy organizations of the JCVI are: The Institute for Genomic Research (TIGR), The Center for the Advancement of Genomics (TCAG), the Institute for Biological Energy Alternatives (IBEA), the Joint Technology Center (JTC), and the J. Craig Venter Science Foundation. The JCVI is a 501 (c) (3) organization. For additional information, please visit http://www.jcvi.org/cms/home/.

About RainDance Technologies, Inc.
RainDance Technologies Inc. is a provider of innovative microdroplet-based solutions for human health and disease research. The speed and simplicity of the company’s exciting new technology platform enable researchers to design experiments in ways that were previously unaffordable or unimaginable. The company’s technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt proven assays for high-speed workflows with minimized process-induced bias or error.

RainDance’s initial application will focus on the targeted resequencing of the human genome — one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England and the ESPCI in Paris.

For more information, please visit http://www.raindancetech.com/.

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Public Relations contact: Tiziani Whitmyre, Inc., www.tizinc.com/services/public-relations/

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